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Uganda and Kenya

Peste des Petits Ruminants Vaccine Associate Award

Principal Investigator (PI) and Lead Institution

Dr. Adegbola Adesogan, University of Florida

Co-PI and Collaborator Institutions

  • Dr. Jeff Mariner, Tufts University (Cummings School of Veterinary Medicine)
  • Dr. Frank Mwiine, Makerere University (College of Veterinary Medicine, Animal Resources and Biosecurity [COVAB])
  • Ms. Ivetta Ouvry, Mercy Corps - Uganda
  • Target country institutions and authorities


Peste des petits ruminants (PPR) is a highly infectious viral disease of small ruminants, primarily domestic sheep and goats. The disease affects around 1.7 billion sheep and goats in 76 countries. It causes a staggering USD 1.45-2.10 billion in losses annually to 330 million of the world’s poorest people, often women, many of whom are food insecure and malnourished. Hence, eradicating PPR will reduce the morbidity and mortality caused by the disease and thus help improve food security, nutrition, and the incomes of millions of poor farmers via animal-source food consumption. Eradicating PPR has become a critical priority of the international community as emphasized at the 2015 International Conference on Control and Eradication of PPR.  Given the relatedness of the PPR and Rinderpest viruses and the fact that they have occurred in similar environments, strategies for PPR control and eradication of PPR should be informed by the lessons learned from the 2011 Rinderpest eradication. Results are expected to support and inform PPR control and eradication efforts worldwide.     

The purpose of this project is to assess innovative approaches to PPR control using thermostable PPR vaccine and to build capacity to scale the vaccine across a broad region where the disease is endemic. The project will use a combination of tools and approaches which proved successful in the RP eradication, including the thermostable vaccine, community animal health worker (CAHW) based vaccination systems, participatory epidemiology (PE) to gather intelligence for targeting vaccination, and use of modeling to target areas with the highest disease transmission.

Photo credit: S. Hendrickx

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